Christina Applegate has announced that she is set to release a new memoir titled You With The Sad Eyes amid her ongoing multiple sclerosis (MS) battle.
The Dead To Me star, 53 - who recently gave a heartbreaking health update a few months earlier - expressed that she made the decision to pen the book when she was 'forced to slow down.'
Her upcoming memoir was acquired by Little, Brown And Company and is slated to hit shelves later next year in March 2026.
Applegate gets candid about her life - including her health journey, tumultuous upbringing in Lauren Canyon, struggles with insecurities, and suffering from past abuse and assault.
'I've had a career in TV and film since I was 3 years old, and I loved it. But with MS, all the things I thought were important shifted,' the Emmy-nominated actress said began in a statement, per People.
'For a long time, it felt impossible to find the meaning in everything I've been through, but for the first time in my life I've been able to stop and reflect.'
Christina then admitted that it was 'scary' to 'to tell it all' in her candid memoir.
'But no matter how dark it gets, I wrote this because I truly believe that books can make people feel less alone.'
The star - who is also known for starring in projects such as Married...With Children -further explained to readers that her book 'won't be some big violin scratching for my life.'
Applegate continued, 'But it will be real. It will be filled with the ups and downs, the humor and grief of life. So here I am. Real me. Lots to say.'
Bryn Clark - the executive editor at Little,Brown and Company - offered a glimpse into what fans can expect with the Hollywood star's memoir.
'As an editor, I'm always chasing the elusive feeling of "I have to have this." You only know it when you see it, and I knew Christina's book was it the second I read her opening words.'
Clark added,'Christina speaks to the power of embracing the messiness and temporality of life instead of hiding behind the plastic veneer of our modern world. We have no time to waste on falsehoods and perfection.'
Along with opening up about her childhood and life in the spotlight, Applegate also discusses her experience with MS.
According to an official description, the Anchorman star 'will unveil the full story of her years in the public eye, and the painful moments the public didn't see.'
The memoir also 'boldly presents a formidable and iconoclastic woman who has had to let go of her acting career, of her ability to dance, of her sense of physical power, but has always fought to find a new and even more fulfilling way of being.'
'The pain will be matched by the joy, the losses mitigated by the extraordinary, the weight of life lifted by Applegate's signature comedic genius...'
Last year in July, Christina confirmed that she was working on the book during an episode of her MeSsy podcast.
Applegate kicked off her entertainment career as a baby in the early 70s when she appeared in an episode of Days Of Our Lives.
She would go on to take on minor roles in shows such as Family Ties, The New Leave It To Beaver, Heart Of The City and 21 Jump Street.
From 1987 through 1997, the actress portrayed the character of Kelly Bundy in the sitcom Married...With Children.
Throughout the 90s, Christina additionally appeared on the big screen in movies including Don't Tell Mom The Babysitter's Dead (1991) and Mars Attacks! (1996).
The mom-of-one also took on a role in the Anchorman franchise - such as Anchorman: The Legend Of Ron Burgundy (2003) and the sequel Anchorman 2: The Legend Continues (2013).
From 2019 through 2022, she played Jen Harding in the critically-acclaimed series Dead To Me alongside Linda Cardellini and James Marsden.
Applegate garnered both Emmy and Golden Globe nominations based on her performance in the show.
In 2021, the actress announced that she had been diagnosed with MS - a 'disease that causes breakdown of the protective covering of nerves' which 'can cause numbness, weakness, trouble walking, vision changes and other symptoms,' per Mayo Clinic.
Christina took a step away from acting to focus on her health battle - and last year she reflected on her podcast how she misses it.
'I do miss that because in all honesty, the only thing I ever had my entire life was work,' she explained.
'I grew up on sets...The inner workings, the outer workings of being on a set is all I really know. I love that place.'
And a few months earlier in May, Applegate gave a heartbreaking health update and revealed that she doesn't 'leave the house anymore.'
During an appearance on Conan O'Brien Needs A Friend, the star admitted, 'I don't really leave the house anymore.'
'If people saw what my life was like on the daily, they wouldn't they wouldn't be able to do it. Because I can sometimes not do it. It's really, really hard.'
She added,
'The first thing that I hear from people is how did you get it? Meaning I must have done something wrong in my life to have this disease, I did it to myself. It’s like I had breast cancer as well so, oh you must have done something.'That stigma, I’m used to it now but it was so hard to swallow for a while because why the f* would you think that I would do something to have this, because this is the worst thing I’ve ever had in my life.'
The actress candidly expressed,
'It’s the worst thing I’ve ever gone through.'
And a few months earlier in May, Applegate gave a heartbreaking health update and revealed that she doesn't 'leave the house anymore'; seen in 2023 in L.A.
Christina explained what a bad day looks for her and said,
'to go to the bathroom is like walking on needles and hot lava so I haven’t really been able to get out of my bed today.'
The star then shared early symptoms she had, such as numbness and also losing her balance.
'Eventually over months it went from my toes to my ankles to from my knees down. Selma Blair said can you please go to the neurologist and I was like there’s no way that both of us from the same movie have MS.'
'I was losing balance, but the pain was extraordinary. And when I say numb, it’s numb, but it hurts,' she continued.