The surprise overnight US attack on Iran inflicted major damage and destruction on three of its key nuclear sites, senior Pentagon officials said, as the US defense secretary denied that the Trump administration was pursuing a policy of regime change in the Middle East.
In a press conference in Washington, Gen Dan Caine, the chair of the Joint Chiefs of Staff, detailed operation "Midnight Hammer" in which seven B-2 Spirit bombers flew 18 hours from the United States to sites in Iran to drop 14 GBU-57 Massive Ordnance Penetrators in strikes that they said caused "extremely severe damage" to Iranian uranium enrichment facilities at Fordow, Natanz, and Isfahan.
Caine said it was not clear whether Iran retained some nuclear capability and stopped short of using the same language as Donald Trump, who said that the sites had been "completely and totally obliterated".
Trump announced the US intervention last night, directly joining Israel's effort to destroy Iran's nuclear programme in a risky gambit that triggered alarm across the world and raised fears of a wider regional conflict.
Satellite imagery of the attack site from Maxar Technologies showed six fresh craters at the Fordow nuclear enrichment site, probably the entry point for the "bunker buster" bombs meant to penetrate deep into the facility before detonation.
The scale of the damage underground was not yet confirmed, Caine said. Iranian sources were quick to deny that the country's nuclear programme was devastated, as its leaders condemned the US strikes and warned they would have long-term repercussions for the region and the global order.
Iran launched about 20 ballistic missiles at Israel on Sunday morning, triggering country-wide air raid sirens and injuring 16 people.
Iran's supreme leader, Ayatollah Ali Khamenei, in a recorded statement aired on state television after the strikes: "The Iranian nation is not one to surrender. Americans should know that any military involvement by the US will undoubtedly result in irreparable damage to them."
Iran's foreign minister, Abbas Araghchi, said diplomacy was not an option after the US attack and that Iran "reserves all rights to defend its security, its interests and its people".
"My country has been under attack, and we have to respond based on our legitimate right to self-defence. We will do that for as long as needed and necessary," he told reporters at a press conference in Istanbul on Sunday.
Araghchi also said the US had "blown up diplomacy" that Tehran was engaged in with Europe and said he would meet Russian president Vladimir Putin in Moscow on Monday.
Iran's parliament on Sunday approved a measure allowing the country's leadership to close the strait of Hormuz, a crucial shipping route from the Persian Gulf to the Gulf of Oman and Arabian Sea that handles about 26% of the global oil trade. While the final decision rests with the country's leadership and not its pliant legislature, the decision indicated an Iranian threat to disrupt global energy shipping as a potential retaliation to the strike.
It was unclear whether an Iranian response would include its network of proxies across the Middle East, including militias such as Hezbollah in Lebanon and the Houthis in Yemen. On Saturday, the Houthi spokesperson Yahya Saree pledged to attack US ships and warships in the Red Sea if the US intervened in Iran, despite a May ceasefire between the US and the Yemeni militia.
US officials said that they were sending signals to Iran to encourage it to negotiate rather than launch a retaliation that could escalate into a protracted war.
Pete Hegseth, the defense secretary, denied that the US was pursuing a policy of regime change in Iran. "This mission was not and has not been about regime change," Hegseth said.
"Anything can happen in conflict. We acknowledge that. But the scope of this was intentionally limited. That's the message that we're sending. With the capabilities of the American military nearly unlimited."
The US vice-president, JD Vance, who has been an outspoken opponent of US military interventions, said during an interview on MSNBC that the US was "not at war with Iran, we're at war with Iran's nuclear programme".
Speaking from the White House last night, Trump said: "Our objective was the destruction of Iran's nuclear enrichment capacity and a stop to the nuclear threat posed by the world's number one state sponsor of terror. Tonight, I can report to the world that the strikes were a spectacular military success. Iran's key nuclear enrichment facilities have been completely and totally obliterated."
"There will be either peace or there will be tragedy for Iran far greater than we have witnessed over the last eight days. Remember, there are many targets left. Tonight's was the most difficult of them all by far, and perhaps the most lethal. But if peace does not come quickly, we will go after those other targets with precision, speed and skill."
The Israeli prime minister, Benjamin Netanyahu, hailed the strikes. "Congratulations, President Trump; your bold decision to target Iran's nuclear facilities with the awesome and righteous might of the United States will change history," he said in a video statement.
Trump also said that he and Netanyahu had "worked as a team like perhaps no team has ever worked before, and we've gone a long way to erasing this horrible threat to Israel".
Previously, Iranian officials said that any US involvement would trigger an attack on US military bases in the Middle East, which host thousands of US troops across at least eight countries.
After Iran's barrage of missiles, Israeli warplanes began strikes in western Iran, hitting missile launchers and Iranian soldiers, the Israeli military said.
In Iran, the media played down the US strikes, with the state-run IRNA news agency acknowledging early on Sunday an attack on the country's Fordow nuclear site, but saying it was evacuated beforehand. The semi-official Fars news agency, which is close to the Revolutionary Guards, quoted another official saying air defences opened fire near Isfahan and explosions had been heard.
Later, Iran's atomic agency said that the country would carry on with its nuclear activities despite the US attacks on key facilities. The Iranian member of parliament Mohammad Manan Raisi, representing the city of Qom where Fordow is located, said that the damage to the nuclear facility was not major and "only on the ground, which can be restored".
The International Atomic Energy Agency said there had been "no increase in off-site radiation levels" after the attacks on the three nuclear sites.
Israel has been launching strikes on Iran for two weeks. It has sought to systematically eradicate the country's air defences and offensive missile capabilities and damage its nuclear enrichment facilities.
US and Israeli officials have said 13,500kg (30,000lb) bunker buster bombs that US stealth bombers alone can carry offered the best chance of destroying heavily fortified sites connected to the Iranian nuclear programme buried deep underground at Fordow.