Three friends hope to complete the missing link in a 17,000-mile mountain bike challenge they did 40 years ago.
Sophie Trafford, Rona Hulbert and Craig Swan met at Aberdeen University and were in their 20s when they cycled from Punta Arenas in Chile to Anchorage in Alaska.
There was no road in 1985 through a remote section of Patagonia in southern Chile and the trio had to take a ferry.
The 62-year-olds have reunited and are returning to Chile this month to cycle almost 800 miles (1,300km), following a road built through the area since their original adventure.
Forty years ago, the friends witnessed war in Central America, coped with illness, earthquakes and robbers along the way.
They were unable to travel through Argentina due to tensions between the country and the UK following the Falklands War in 1982.
The trip lasted a year and they raised £70,000 for Breast Cancer Research.
When they returned home, they were named BBC Scotland's Scots of the Year for 1985-86 in recognition of their fundraising.
The new bike ride will raise money for a Maggie's cancer centre in Forth Valley and the Epilepsy Research Institute.
Rona, from Newmills, Fife, said: "We are all in our 60s and far being in from peak condition. We haven't been back on bikes in 40 years.
"Southern Patagonia in October will be cold, wet, and windy, and the idea of camping for five weeks while we cycle the 1,200 kms is daunting to say the least."
Rona, who had a career in retail in South Africa and the UK, added: "With our own families raised and flown the nest, and having all been pensioned off, we wondered if we could get the old team back together, get back on our bikes and complete the journey.
"Maggie's supported me on my own difficult cancer journey and this is a chance to help them."
Sophie, who worked in corporate finance and lives in Balfron, near Stirling, said: "It's quite a prospect, but an exciting and emotional one.
"We are in-training to get ready, but cycling long distances daily and camping each night for weeks is a very different prospect at the age of 62 than it was as 22-year-olds."
Sophie's son Hector died from sudden unexpected death in epilepsy (SUDEP).
She said: "More research is needed to identify the causes and ways to prevent SUDEP deaths. Donations will be split evenly between both charities."
Former BBC journalist Craig Swan, who lives in Grantown on Spey in the Highlands, said like many people all three had been affected by deaths of loved ones.
He added: "Life can be hard. This is an opportunity for all of us to finish what we started 40 years ago, and at the same time help causes very close to our hearts."
The friends will cycle south along the whole length of a road called Carretera Austral.
They hope to reach Villa O'Higgins, a small town in southern Chile, next month.